产品名称
TAF I p48 Rabbit Polyclonal Antibody
别名
TAF1A; TATA box-binding protein-associated factor RNA polymerase I subunit A; RNA polymerase I-specific TBP-associated factor 48 kDa; TAFI48; TATA box-binding protein-associated factor 1A; TBP-associated factor 1A; Transcription factor SL1;
蛋白名称
TATA box-binding protein-associated factor RNA polymerase I subunit A
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9015
Human Swissprot No.
Q15573
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q15573/entry
Mouse Swissprot No.
P97357
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P97357
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=360893
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q3B7U2
免疫原
The antiserum was produced against synthesized peptide derived from human TAF1A. AA range:301-350
特异性
TAF I p48 Polyclonal Antibody detects endogenous levels of TAF I p48 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a subunit of the RNA polymerase I complex, Selectivity Factor I (SLI). The encoded protein is a TATA box-binding protein-associated factor that plays a role in the assembly of the RNA polymerase I preinitiation complex. Alternate splicing results in multiple transcript variants encoding multiple isoforms.[provided by RefSeq, Jan 2011],
功能
function:Component of the transcription factor SL1/TIFIB complex involved in the assembly of the PIC (preinitiation complex).,subunit:Component of the transcription factor SL1/TIFIB complex which is composed of TBP and at least TAF1A, TAF1B and TAF1C. In the complex, interacts directly with TBP, TAF1B and TAF1C. Interaction of the SL1/TIFIB subunits with TBP excludes interaction with the transcription factor IID (TFIID) subunits. This mutually exclusive binding directs the formation of promoter and RNA polymerase-selective TBP-TAF complexes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
