产品名称
TAB182 Rabbit Polyclonal Antibody
别名
TNKS1BP1; KIAA1741; TAB182; 182 kDa tankyrase-1-binding protein
蛋白名称
182 kDa tankyrase-1-binding protein
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=85456
Human Swissprot No.
Q9C0C2
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9C0C2/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=228140
Mouse Swissprot No.
P58871
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P58871
免疫原
The antiserum was produced against synthesized peptide derived from human TNKS1BP1. AA range:1601-1650
特异性
TAB182 Polyclonal Antibody detects endogenous levels of TAB182 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
PTM:ADP-ribosylated by TNKS1 (in vitro).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin.,subunit:Binds to the ANK repeat domain of TNKS1 and TNKS2.,tissue specificity:Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes.,
组织表达
Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes.
细胞定位
Nucleus. Cytoplasm, cytoskeleton. Chromosome. Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin.
功能
PTM:ADP-ribosylated by TNKS1 (in vitro).,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,subcellular location:Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin.,subunit:Binds to the ANK repeat domain of TNKS1 and TNKS2.,tissue specificity:Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
