产品名称
T3JAM Rabbit Polyclonal Antibody
别名
TRAF3IP3; T3JAM; TRAF3-interacting JNK-activating modulator; TRAF3-interacting protein 3
蛋白名称
TRAF3-interacting JNK-activating modulator
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=80342
Human Swissprot No.
Q9Y228
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9Y228/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=215243
Mouse Swissprot No.
Q8C0G2
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8C0G2
免疫原
The antiserum was produced against synthesized peptide derived from human T3JAM. AA range:251-300
特异性
T3JAM Polyclonal Antibody detects endogenous levels of T3JAM protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multi-protein assembly containing the phosphatase 2A catalytic subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],
组织表达
Blood,Lung adenocarcinoma,
细胞定位
Cell membrane . Golgi apparatus membrane ; Single-pass type IV membrane protein . Lysosome membrane . Mitochondrion outer membrane . Accumulates on the mitochondria after virus infection. .
功能
function:May function as an adapter molecule that regulates TRAF3-mediated JNK activation.,subunit:Binds to the isoleucine zipper of TRAF3 via its coiled-coil domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
