产品名称
T2R45 Rabbit Polyclonal Antibody
别名
TAS2R45; GPR59; Taste receptor type 2 member 45; T2R45; G-protein coupled receptor 59
蛋白名称
Taste receptor type 2 member 45
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=259291
Human Swissprot No.
P59539
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P59539/entry
免疫原
The antiserum was produced against synthesized peptide derived from human TAS2R45. AA range:221-270
特异性
T2R45 Polyclonal Antibody detects endogenous levels of T2R45 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.,miscellaneous:Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.,
组织表达
Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
细胞定位
Membrane; Multi-pass membrane protein.
功能
function:Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.,miscellaneous:Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.