产品名称
T2R39 Rabbit Polyclonal Antibody
别名
TAS2R39; Taste receptor type 2 member 39; T2R39; Taste receptor type 2 member 57; T2R57
蛋白名称
Taste receptor type 2 member 39
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=259285
Human Swissprot No.
P59534
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P59534/entry
Mouse Swissprot No.
Q7TQA5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q7TQA5
免疫原
The antiserum was produced against synthesized peptide derived from human TAS2R39. AA range:218-267
特异性
T2R39 Polyclonal Antibody detects endogenous levels of T2R39 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a bitter taste receptor that detects green tea catechins, soy isoflavones, and theaflavins. The encoded protein is gustducin-linked and may activate alpha gustducin. This gene is intronless. [provided by RefSeq, Dec 2015],
组织表达
Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
细胞定位
Membrane; Multi-pass membrane protein.
功能
function:Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.,miscellaneous:Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
