BD-PT4505

T2R13 Rabbit Polyclonal Antibody

TAS2R13; Taste receptor type 2 member 13; T2R13; Taste receptor family B member 3; TRB3

常规抗体

TAS2R13

Taste receptor type 2 member 13

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

50838

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=50838

Q9NYV9

http://www.uniprot.org/uniprotkb/Q9NYV9/entry

Q7M720

http://www.uniprot.org/uniprot/Q7M720

The antiserum was produced against synthesized peptide derived from human TAS2R13. AA range:123-172

T2R13 Polyclonal Antibody detects endogenous levels of T2R13 protein.

WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000

35kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008],

Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.

Membrane; Multi-pass membrane protein.

Taste transduction;

function:Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.,miscellaneous:Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.