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T1R3 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT4502
产品名称
T1R3 Rabbit Polyclonal Antibody
别名
TAS1R3; T1R3; TR3; Taste receptor type 1 member 3; Sweet taste receptor T1R3
类别
常规抗体
基因名称
TAS1R3
蛋白名称
Taste receptor type 1 member 3
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
83756
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=83756
Human Swissprot No.
Q7RTX0
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q7RTX0/entry
Mouse Swissprot No.
Q925D8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q925D8
免疫原
The antiserum was produced against synthesized peptide derived from human TAS1R3. AA range:326-375
特异性
T1R3 Polyclonal Antibody detects endogenous levels of T1R3 protein.
稀释度
WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
预测分子量
93kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a G-protein coupled receptor involved in taste responses. The encoded protein can form a heterodimeric receptor with TAS1R1 to elicit the umami taste response, or it can bind with TAS1R2 to form a receptor for the sweet taste response. [provided by RefSeq, Nov 2015],
细胞定位
Cell membrane; Multi-pass membrane protein.
信号通路
Taste transduction;
功能
function:Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.,online information:The taste experience -Issue 55 of February 2005,similarity:Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.,subunit:Forms homodimers or heterodimers with TAS1R1 and TAS1R2.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunofluorescence analysis of MCF7 cells, using TAS1R3 Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from Jurkat cells, using TAS1R3 Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of the lysates from HeLa cells using TAS1R3 antibody.

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