产品名称
Syndecan-4 Rabbit Polyclonal Antibody
别名
SDC4; Syndecan-4; SYND4; Amphiglycan; Ryudocan core protein
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6385
Human Swissprot No.
P31431
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P31431/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20971
Mouse Swissprot No.
O35988
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O35988
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24771
Rat Swissprot Link
http://www.uniprot.org/uniprot/P34901
免疫原
The antiserum was produced against synthesized peptide derived from human Syndecan4. AA range:145-194
特异性
Syndecan-4 Polyclonal Antibody detects endogenous levels of Syndecan-4 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan that functions as a receptor in intracellular signaling. The encoded protein is found as a homodimer and is a member of the syndecan proteoglycan family. This gene is found on chromosome 20, while a pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008],
组织表达
Expressed in epithelial and fibroblastic cells.
细胞定位
[Isoform 1]: Membrane ; Single-pass type I membrane protein . Secreted . Shedding of the ectodomain produces a soluble form. .; [Isoform 2]: Secreted.
信号通路
ECM-receptor interaction;Cell adhesion molecules (CAMs);
功能
function:Cell surface proteoglycan that bears heparan sulfate.,function:Cell surface proteoglycan.,similarity:Belongs to the syndecan proteoglycan family.,subunit:Homodimer. Interacts with CDCP1, with GIPC PDZ domain and with NUDT16L1/SDOS (By similarity). Interacts with SDCBP.,tissue specificity:Expressed in epithelial and fibroblastic cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
