产品名称
Syndecan-2 Rabbit Polyclonal Antibody
别名
SDC2; HSPG1; Syndecan-2; SYND2; Fibroglycan; Heparan sulfate proteoglycan core protein; HSPG; CD antigen CD362
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6383
Human Swissprot No.
P34741
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P34741/entry
Mouse Swissprot No.
P43407
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P43407
免疫原
The antiserum was produced against synthesized peptide derived from human SDC2. AA range:81-130
特异性
Syndecan-2 Polyclonal Antibody detects endogenous levels of Syndecan-2 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008],
组织表达
Brain,Embryo,Lung fibroblast,Muscle,Testis,
细胞定位
Membrane; Single-pass type I membrane protein.
信号通路
ECM-receptor interaction;Cell adhesion molecules (CAMs);
功能
function:Cell surface proteoglycan that bears heparan sulfate.,function:Cell surface proteoglycan.,similarity:Belongs to the syndecan proteoglycan family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
