产品名称
Synaptotagmin XIII Rabbit Polyclonal Antibody
别名
SYT13; KIAA1427; Synaptotagmin-13; Synaptotagmin XIII; SytXIII
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57586
Human Swissprot No.
Q7L8C5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q7L8C5/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=80976
Mouse Swissprot No.
Q9EQT6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9EQT6
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=80977
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q925B5
免疫原
The antiserum was produced against synthesized peptide derived from human SYT13. AA range:321-370
特异性
Synaptotagmin XIII Polyclonal Antibody detects endogenous levels of Synaptotagmin XIII protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
synaptotagmin 13(SYT13) Homo sapiens This gene encodes a member of the large synaptotagmin protein family. Family members have an extracellular N-terminal transmembrane domain and a cytoplasmic C terminus with two tandem C2 domains (C2A and C2B). Synaptotogmin family members can form homo- and heteromeric complexes with each other. They also have different biochemical properties and developmental profiles, and patterns of tissue distribution. Synaptotagmins function as membrane traffickers in multicellular organisms. Two alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011],
组织表达
Expressed in brain, pancreas and kidney.
细胞定位
Membrane ; Single-pass membrane protein .
功能
domain:The first C2 domain/C2A does not mediate Ca(2+)-dependent phospholipid binding.,domain:The second C2 domain/C2B domain binds phospholipids regardless of whether calcium is present.,function:May be involved in transport vesicle docking to the plasma membrane.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Interacts with NRXN1.,tissue specificity:Expressed in brain, pancreas and kidney.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
