产品名称
Synaptotagmin X Rabbit Polyclonal Antibody
别名
SYT10; Synaptotagmin-10; Synaptotagmin X; SytX
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=341359
Human Swissprot No.
Q6XYQ8
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q6XYQ8/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54526
Mouse Swissprot No.
Q9R0N4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9R0N4
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=60567
Rat Swissprot Link
http://www.uniprot.org/uniprot/O08625
免疫原
Synthesized peptide derived from Synaptotagmin X . at AA range: 380-460
特异性
Synaptotagmin X Polyclonal Antibody detects endogenous levels of Synaptotagmin X protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Homodimer. Can also form heterodimers.,tissue specificity:Expressed only in pancreas, lung and kidney.,
组织表达
Expressed only in pancreas, lung and kidney.
细胞定位
Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass membrane protein . Localizes to neuronal vesicles containing IGF1 that are not enriched at synapses. Does not colocalize with synaptic vesicles or with the Golgi apparatus. .
功能
cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Homodimer. Can also form heterodimers.,tissue specificity:Expressed only in pancreas, lung and kidney.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
