产品名称
SWAP Rabbit Polyclonal Antibody
别名
SFSWAP; SFRS8; SWAP; Splicing factor; suppressor of white-apricot homolog; Splicing factor, arginine/serine-rich 8; Suppressor of white apricot protein homolog
蛋白名称
Splicing factor suppressor of white-apricot homolog
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6433
Human Swissprot No.
Q12872
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q12872/entry
Mouse Swissprot No.
Q3USH5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3USH5
免疫原
The antiserum was produced against synthesized peptide derived from human SFRS8. AA range:201-250
特异性
SWAP Polyclonal Antibody detects endogenous levels of SWAP protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a human homolog of Drosophila splicing regulatory protein. This gene autoregulates its expression by control of splicing of its first two introns. In addition, it also regulates the splicing of fibronectin and CD45 genes. Two transcript variants encoding different isoforms have been identified. [provided by RefSeq, May 2012],
组织表达
Brain,Epithelium,Eye,Placenta,Skin,
功能
function:May function as an alternative splicing regulator. Regulate its own expression at the level of RNA processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction with other R/S-containing splicing factors.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 2 SURP motif repeats.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
