BD-PT4463

Stonin-1 Rabbit Polyclonal Antibody

STON1; SALF; SBLF; STN1; Stonin-1; Stoned B-like factor

常规抗体

STON1

Stonin-1

WB

Human,Rat,Mouse

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

11037

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11037

Q9Y6Q2

http://www.uniprot.org/uniprotkb/Q9Y6Q2/entry

Q8CDJ8

http://www.uniprot.org/uniprot/Q8CDJ8

The antiserum was produced against synthesized peptide derived from human STON1. AA range:686-735

Stonin-1 Polyclonal Antibody detects endogenous levels of Stonin-1 protein.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

83kD

-20°C/1 year

Polyclonal, Rabbit,IgG

stonin 1(STON1) Homo sapiens Endocytosis of cell surface proteins is mediated by a complex molecular machinery that assembles on the inner surface of the plasma membrane. This gene encodes one of two human homologs of the Drosophila melanogaster stoned B protein. This protein is related to components of the endocytic machinery and exhibits a modular structure consisting of an N-terminal proline-rich domain, a central region of homology specific to the human stoned B-like proteins, and a C-terminal region homologous to the mu subunits of adaptor protein (AP) complexes. Read-through transcription of this gene into the neighboring downstream gene, which encodes TFIIA-alpha/beta-like factor, generates a transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010],

Ubiquitous.

Cytoplasm . Membrane . Some fraction is membrane-associated.

Basal transcription factors;

caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:May be involved in the endocytic machinery.,function:May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription.,miscellaneous:In contrast to other members of the family, it does not contain NPF (Asn-Pro-Phe) sites and thereby does not interact with EPS15, EPS15R and ITSN1.,sequence caution:Chimeric cDNA. The biological existence and relevance of this product of both SALF (AC Q9Y6Q2) and GTF2A1LF genes, creating a chimeric protein of 1182 residues is uncertain.,sequence caution:Chimeric cDNA. The biological existence and relevance of this product of both SALF and GTF2A1LF (AC Q9UNN4) genes, which codes for a chimeric protein of 1182 residues is uncertain.,similarity:Belongs to the Stoned B family.,similarity:Belongs to the TFIIA subunit 1 family.,similarity:Contains 1 MHD (mu homology) domain.,similarity:Contains 1 SHD (stonin homology) domain.,subcellular location:Some fraction is membrane-associated.,tissue specificity:Testis specific.,tissue specificity:Ubiquitous.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.