BD-PT4457-STEAP1 Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

STEAP1 Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT4457

产品名称

STEAP1 Rabbit Polyclonal Antibody

别名

STEAP1; PRSS24; STEAP; Metalloreductase STEAP1; Six-transmembrane epithelial antigen of prostate 1

类别

常规抗体

基因名称

STEAP1

蛋白名称

Metalloreductase STEAP1

推荐应用

反应种属

Human,Rat,Mouse

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

26872

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26872

Human Swissprot No.

Q9UHE8

Human Swissprot Link

http://www.uniprot.org/uniprotkb/Q9UHE8/entry

Mouse Swissprot No.

Q9CWR7

Mouse Swissprot Link

http://www.uniprot.org/uniprot/Q9CWR7

免疫原

The antiserum was produced against synthesized peptide derived from human STEAP1. AA range:31-80

特异性

STEAP1 Polyclonal Antibody detects endogenous levels of STEAP1 protein.

稀释度

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

预测分子量

36kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions. [provided by RefSeq, Jul 2008],

组织表达

Ubiquitously expressed. Highly expressed in prostate tumors.

细胞定位

Endosome membrane ; Multi-pass membrane protein .

功能

cofactor:FAD.,function:Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor.,similarity:Belongs to the STEAP family.,similarity:Contains 1 ferric oxidoreductase domain.,tissue specificity:Ubiquitously expressed. Highly expressed in prostate tumors.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunohistochemistry analysis of STEAP1 antibody in paraffin-embedded human prostate carcinoma tissue.

Western blot analysis of lysate from A549, using STEAP1 antibody.

Western Blot analysis of various cells using STEAP1 Polyclonal Antibody

Immunohistochemical analysis of paraffin-embedded Human prostate cancer. Antibody was diluted at 1:100（4°,overnight）. High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl （right） obtaned from antibody was pre-absorbed by immunogen peptide.