产品名称
GATA-2/3 (Acetyl-Lys336/304) Rabbit Polyclonal Antibody
蛋白名称
GATA binding protein 2/GATA binding protein 3
反应种属
Human:K336/304,Mouse:K336/304,Rat:K336/305
存储缓冲液
PBS, pH 7.4, containing 0.02% New type preservative N as Preservative and 50% Glycerol.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2624
Human Swissprot No.
P23769/P23771
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P23769/entry
免疫原
Synthesized acetyl-peptide from human protein at AA range: 320-390
特异性
This antibody detects endogenous levels of GATA-2/3 at Human:K336/304;Mouse:K336/304;Rat:K336/305, It doesn't reacte with total protein.
稀释度
WB 1:500-10000 ELISA: 1:10000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009],
功能
function:Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'-AGATAG-3'.,sequence caution:Several sequencing errors.,similarity:Contains 2 GATA-type zinc fingers.,tissue specificity:Endothelial cells.,
纯化
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
