BD-PT4421-SRp75 Rabbit Polyclonal Antibody-现货抗体产品库武汉枢密脑科学技术有限公司

SRp75 Rabbit Polyclonal Antibody

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产品基本信息

产品货号

BD-PT4421

产品名称

SRp75 Rabbit Polyclonal Antibody

别名

SRSF4; SFRS4; SRP75; Serine/arginine-rich splicing factor 4; Pre-mRNA-splicing factor SRP75; SRP001LB; Splicing factor; arginine/serine-rich 4

类别

常规抗体

基因名称

SRSF4

蛋白名称

Serine/arginine-rich splicing factor 4

推荐应用

反应种属

Human,Mouse

浓度

1 mg/ml

存储缓冲液

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Human Gene ID

6429

Human Gene Link

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6429

Human Swissprot No.

Q08170

Human Swissprot Link

http://www.uniprot.org/uniprotkb/Q08170/entry

Mouse Swissprot No.

Q8VE97

Mouse Swissprot Link

http://www.uniprot.org/uniprot/Q8VE97

免疫原

The antiserum was produced against synthesized peptide derived from human SFRS4. AA range:111-160

特异性

SRp75 Polyclonal Antibody detects endogenous levels of SRp75 protein.

稀释度

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

预测分子量

57kD

运输及保存条件

-20°C/1 year

宿主

Polyclonal, Rabbit,IgG

背景介绍

This gene encodes a member of the arginine/serine-rich splicing factor family. The encoded protein likely functions in mRNA processing. [provided by RefSeq, Feb 2009],

组织表达

Aorta endothelial cell,Cerebrum,Epithelium,Lymph,

细胞定位

Nucleus speckle .

信号通路

Spliceosome;

功能

function:A probable role in alternative splice site selection during pre-mRNA splicing.,PTM:Extensively phosphorylated on serine residues in the RS domain.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 2 RRM (RNA recognition motif) domains.,subunit:Found in a pre-mRNA splicing complex with SFRS4, SFRS5, SNRNP70, SNRPA1, SRRM1 and SRRM2. Interacts with PNN.,

期货

现货

纯化

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from LOVO cells, using SFRS4 Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using SRp75 Polyclonal Antibody diluted at 1：1000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit （SC-003,Inventbiotech,MN,USA）.

Immunohistochemical analysis of paraffin-embedded Human thyroid gland. Antibody was diluted at 1:100（4°,overnight）. High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval. Negetive contrl （right） obtaned from antibody was pre-absorbed by immunogen peptide.