产品名称
SRp46 Rabbit Polyclonal Antibody
别名
SRSF8; SFRS2B; SRP46; Serine/arginine-rich splicing factor 8; Pre-mRNA-splicing factor SRP46; Splicing factor SRp46; Splicing factor; arginine/serine-rich 2B
蛋白名称
Serine/arginine-rich splicing factor 8
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10929
Human Swissprot No.
Q9BRL6
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9BRL6/entry
免疫原
The antiserum was produced against synthesized peptide derived from human SFRS2B. AA range:31-80
特异性
SRp46 Polyclonal Antibody detects endogenous levels of SRp46 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of a family of proteins containing a ribonucleoprotein (RNP)-type RNA binding motif and a carboxyl-terminal arginine-serine-rich (RS) domain. The encoded protein functions as a pre-mRNA splicing factor. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],
组织表达
Strongly expressed in pancreas, spleen and prostate. Weakly expressed in lung, liver and thymus.
功能
function:Invovlved in pre-mRNA alternative splicing.,PTM:Phosphorylated.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,tissue specificity:Strongly expressed in pancreas, spleen and prostate. Weakly expressed in lung, liver and thymus.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
