产品名称
Spi-C Rabbit Polyclonal Antibody
别名
SPIC; Transcription factor Spi-C
蛋白名称
Transcription factor Spi-C
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=121599
Human Swissprot No.
Q8N5J4
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8N5J4/entry
Mouse Swissprot No.
Q6P3D7
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q6P3D7
免疫原
The antiserum was produced against synthesized peptide derived from human SPIC. AA range:131-180
特异性
Spi-C Polyclonal Antibody detects endogenous levels of Spi-C protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene regulates the development of red pulp macrophages, which are necessary for iron homeostasis and the recycling of red blood cells. [provided by RefSeq, Aug 2016],
组织表达
Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.
功能
function:Probable transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer.,similarity:Belongs to the ETS family.,similarity:Contains 1 ETS DNA-binding domain.,subunit:Binds DNA as a monomer.,tissue specificity:Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
