产品名称
Sp2 Rabbit Polyclonal Antibody
别名
SP2; KIAA0048; Transcription factor Sp2
蛋白名称
Transcription factor Sp2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6668
Human Swissprot No.
Q02086
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q02086/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=78912
Mouse Swissprot No.
Q9D2H6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9D2H6
免疫原
The antiserum was produced against synthesized peptide derived from human SP2. AA range:471-520
特异性
Sp2 Polyclonal Antibody detects endogenous levels of Sp2 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters. [provided by RefSeq, Jul 2008],
组织表达
Bone marrow,Brain,Lung,Lymph,Spleen,
功能
function:Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites.,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
