产品名称
Sos 2 Rabbit Polyclonal Antibody
别名
SOS2; Son of sevenless homolog 2; SOS-2
蛋白名称
Son of sevenless homolog 2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6655
Human Swissprot No.
Q07890
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q07890/entry
Mouse Swissprot No.
Q02384
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q02384
免疫原
The antiserum was produced against synthesized peptide derived from human SOS2. AA range:631-680
特异性
Sos 2 Polyclonal Antibody detects endogenous levels of Sos 2 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a regulatory protein that is involved in the positive regulation of ras proteins. Mutations in this gene are associated with Noonan Syndrome-9. [provided by RefSeq, Jul 2016],
细胞定位
intracellular,cytosol,
信号通路
MAPK_ERK_Growth;MAPK_G_Protein;ErbB_HER;Chemokine;Dorso-ventral axis formation;Focal adhesion;Gap junction;Jak_STAT;Natural killer cell mediated cytotoxicity;T_Cell_Receptor;B_Cell_Antigen;Fc epsilon RI;Neurotrophin;Regulates Actin and Cytoskeleton;Insuli
功能
function:Promotes the exchange of Ras-bound GDP by GTP.,online information:Son of sevenless entry,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 Ras-GEF domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
