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Somatostatin Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT4365
产品名称
Somatostatin Rabbit Polyclonal Antibody
别名
SST; Somatostatin; Growth hormone release-inhibiting factor
类别
常规抗体
基因名称
SST
蛋白名称
Somatostatin
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
6750
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6750
Human Swissprot No.
P61278
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P61278/entry
Mouse Gene ID
20604
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20604
Mouse Swissprot No.
P60041
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P60041
Rat Gene ID
24797
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24797
Rat Swissprot No.
P60042
Rat Swissprot Link
http://www.uniprot.org/uniprot/P60042
免疫原
The antiserum was produced against synthesized peptide derived from human Somatostatin. AA range:10-59
特异性
Somatostatin Polyclonal Antibody detects endogenous levels of Somatostatin protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
预测分子量
17kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008],
组织表达
Fetal brain,
细胞定位
Secreted .
功能
function:Somatostatin inhibits the release of somatotropin.,online information:Somatostatin entry,pharmaceutical:A synthetic analog known as octreotide or SMS 201-995 is available under the name Sandostatin (Novartis). It is used for the treatment of a variety of disorders including acromegaly and the symptomatic treatment of carcinoid tumors and vasoactive intestinal peptide tumors.,similarity:Belongs to the somatostatin family.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using Somatostatin Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from A549 cells, using Somatostatin Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using Somatostatin Polyclonal Antibody

Western Blot analysis of A549 cells using Somatostatin Polyclonal Antibody

Immunohistochemical analysis of paraffin-embedded Human Gastric fundus. 1, Antibody was diluted at 1:200(4°,overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).

Immunohistochemical analysis of paraffin-embedded Human Gastric fundus. 1, Antibody was diluted at 1:200(4°,overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).

Immunohistochemical analysis of paraffin-embedded Human Gastric fundus. 1, Antibody was diluted at 1:200(4°,overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).

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