产品名称
SNX4 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8723
Human Swissprot No.
O95219
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O95219/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=69150
Mouse Swissprot No.
Q91YJ2
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q91YJ2
免疫原
The antiserum was produced against synthesized peptide derived from human SNX4. AA range:191-240
特异性
SNX4 Polyclonal Antibody detects endogenous levels of SNX4 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2012],
细胞定位
Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Also detected on a juxtanuclear endocytic recycling compartment (ERC). .
功能
function:May be involved in several stages of intracellular trafficking.,similarity:Belongs to the sorting nexin family.,similarity:Contains 1 PX (phox homology) domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
