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SLK Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT4320
产品名称
SLK Rabbit Polyclonal Antibody
别名
SLK; KIAA0204; STK2; STE20-like serine/threonine-protein kinase; STE20-like kinase; hSLK; CTCL tumor antigen se20-9; STE20-related serine/threonine-protein kinase; STE20-related kinase; Serine/threonine-protein kinase 2
类别
常规抗体
基因名称
SLK
蛋白名称
STE20-like serine/threonine-protein kinase
推荐应用
WB
反应种属
Human,Mouse,Rat
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
9748
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9748
Human Swissprot No.
Q9H2G2
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9H2G2/entry
Mouse Gene ID
20874
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20874
Mouse Swissprot No.
O54988
Mouse Swissprot Link
http://www.uniprot.org/uniprot/O54988
Rat Gene ID
54308
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54308
Rat Swissprot No.
O08815
Rat Swissprot Link
http://www.uniprot.org/uniprot/O08815
免疫原
The antiserum was produced against synthesized peptide derived from human SLK. AA range:1151-1200
特异性
SLK Polyclonal Antibody detects endogenous levels of SLK protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
预测分子量
150kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Mediates apoptosis and actin stress fiber dissolution.,PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Proteolytically cleaved by caspase-3.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 422.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 611.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 614.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UVR domain.,tissue specificity:Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle.,
组织表达
Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle.
细胞定位
Cytoplasm .
信号通路
Oocyte meiosis;
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Mediates apoptosis and actin stress fiber dissolution.,PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM:Proteolytically cleaved by caspase-3.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 422.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 611.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 614.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UVR domain.,tissue specificity:Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunofluorescence analysis of HepG2 cells, using SLK Antibody. The picture on the right is blocked with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue, using SLK Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from COLO205 cells, using SLK Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using SLK Polyclonal Antibody diluted at 1:1000

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