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SgK288 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT4272
产品名称
SgK288 Rabbit Polyclonal Antibody
别名
ANKK1; PKK2; SGK288; Ankyrin repeat and protein kinase domain-containing protein 1; Protein kinase PKK2; Sugen kinase 288; SgK288; X-kinase
类别
常规抗体
基因名称
ANKK1
蛋白名称
Ankyrin repeat and protein kinase domain-containing protein 1
推荐应用
WB
反应种属
Human,Rat,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
255239
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=255239
Human Swissprot No.
Q8NFD2
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8NFD2/entry
Mouse Swissprot No.
Q8BZ25
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BZ25
免疫原
The antiserum was produced against synthesized peptide derived from human ANKK1. AA range:321-370
特异性
SgK288 Polyclonal Antibody detects endogenous levels of SgK288 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
预测分子量
84kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009],
组织表达
Highly expressed in brain and weakly expressed in placenta and spinal cord.
功能
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,similarity:Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,similarity:Contains 12 ANK repeats.,tissue specificity:Highly expressed in brain and weakly expressed in placenta and spinal cord.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from HeLa cells, using ANKK1 Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using SgK288 Polyclonal Antibody

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