产品名称
SFRS11 Rabbit Polyclonal Antibody
别名
SRSF11; SFRS11; Serine/arginine-rich splicing factor 11; Arginine-rich 54 kDa nuclear protein; p54; Splicing factor; arginine/serine-rich 11
蛋白名称
Serine/arginine-rich splicing factor 11
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9295
Human Swissprot No.
Q05519
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q05519/entry
免疫原
The antiserum was produced against synthesized peptide derived from human SFRS11. AA range:211-260
特异性
SFRS11 Polyclonal Antibody detects endogenous levels of SFRS11 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Although the function of this protein is not yet known, structure and immunolocalization data suggest that it may play a role in pre-mRNA processing. Alternative splicing results in multiple transcript variants encoding different proteins. In addition, a pseudogene of this gene has been found on chromosome 12.[provided by RefSeq, Sep 2010],
组织表达
Colon endothel,Epithelium,Fetal brain,Hepatoma,Human fetal
细胞定位
Nucleus. Colocalizes with spliceosome components.
功能
function:May function in pre-mRNA splicing.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subcellular location:Colocalizes with spliceosome components.,subunit:Interacts with PUF60.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
