产品名称
SERGEF Rabbit Polyclonal Antibody
别名
SERGEF; DELGEF; GNEFR; Secretion-regulating guanine nucleotide exchange factor; Deafness locus-associated putative guanine nucleotide exchange factor; DelGEF; Guanine nucleotide exchange factor-related protein
蛋白名称
Secretion-regulating guanine nucleotide exchange factor
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26297
Human Swissprot No.
Q9UGK8
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9UGK8/entry
Mouse Swissprot No.
Q80YD6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q80YD6
免疫原
The antiserum was produced against synthesized peptide derived from human SERGEF. AA range:179-228
特异性
SERGEF Polyclonal Antibody detects endogenous levels of SERGEF protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 7 RCC1 repeats.,subunit:Interacts with SEC5. The interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP.,
细胞定位
Cytoplasm . Nucleus .
信号通路
Regulation of Actin Dynamics; AMPK
功能
function:Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 7 RCC1 repeats.,subunit:Interacts with SEC5. The interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
