产品名称
Septin 3 Rabbit Polyclonal Antibody
别名
SEPT3; SEP3; Neuronal-specific septin-3
蛋白名称
Neuronal-specific septin-3
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55964
Human Swissprot No.
Q9UH03
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9UH03/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24050
Mouse Swissprot No.
Q9Z1S5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9Z1S5
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56003
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q9WU34
免疫原
The antiserum was produced against synthesized peptide derived from human SEPT3. AA range:136-185
特异性
Septin 3 Polyclonal Antibody detects endogenous levels of Septin 3 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
septin 3(SEPT3) Homo sapiens This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm. Cytoplasm, cytoskeleton . Cell junction, synapse .
功能
function:Involved in cytokinesis .,induction:Up-regulated during neuronal differentiation.,PTM:Phosphorylated by PKG on serine residues. Phosphorylated by PKG on Ser-91.,similarity:Belongs to the septin family.,subcellular location:Localizes in synaptosomes at dendritic synapses of neurons. Localizes within presynaptic terminals of neurons.,subunit:May assemble into a multicomponent structure.,tissue specificity:Brain specific.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
