产品名称
DRP2 Rabbit Polyclonal Antibody
别名
Dystrophin-related protein 2 (DRP-2)
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.245% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/1821
Human Swissprot No.
Q13474
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q13474/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/13497
Mouse Swissprot No.
Q05AA6
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q05AA6
Rat Gene Link
https://www.uniprot.org/uniprot/66027
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9EPA0
免疫原
Synthesized peptide derived from human DRP2 AA range: 437-487
特异性
This antibody detects endogenous levels of DRP2 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
Members of the dystrophin family of proteins perform a critical role in the maintenance of membrane-associated complexes at points of intercellular contact in vertebrate cells. The protein encoded by this gene is predicted to resemble certain short C-terminal isoforms of dystrophin and dystrophin-related protein 1 (DRP1 or utrophin). DRP2 is expressed principally in the brain and spinal cord. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],
组织表达
Detected in fetal brain.
细胞定位
Cell junction, synapse, postsynaptic density . Cell projection, dendrite . Perikaryon . Cell membrane ; Peripheral membrane protein . Detected in Schwann cells at periaxonal myelin membranes. .
功能
function:Possibly involved in membrane-cytoskeleton interactions of the central nervous system.,similarity:Contains 1 WW domain.,similarity:Contains 1 ZZ-type zinc finger.,similarity:Contains 2 spectrin repeats.,tissue specificity:Brain and spinal cord; very low levels in eye, ovary, epididymis and testis; not in cardiac and skeletal muscle.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
