产品名称
Septin 14 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=346288
Human Swissprot No.
Q6ZU15
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q6ZU15/entry
Mouse Swissprot No.
Q9DA97
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9DA97
免疫原
The antiserum was produced against synthesized peptide derived from human SEPT14. AA range:341-390
特异性
Septin 14 Polyclonal Antibody detects endogenous levels of Septin 14 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
SEPT14 is a member of the highly conserved septin family of GTP-binding cytoskeletal proteins implicated in membrane transport, apoptosis, cell polarity, cell cycle regulation, cytokinesis, and other cellular functions (Peterson et al., 2007 [PubMed 17922164]).[supplied by OMIM, Jul 2008],
组织表达
Testis-specific (at protein level).
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton . Cell projection, axon . Cell projection, dendrite . Perikaryon . Cytoplasm, perinuclear region . Cytoplasmic vesicle, secretory vesicle, acrosome . Colocalizes with actin stress fibers (PubMed:17922164). Expressed in the perinuclear rim and manchette structure in early elongating spermatids during spermiogenesis (By similarity). .
功能
function:Involved in cytokinesis .,similarity:Belongs to the septin family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
