产品名称
Septin 1 Rabbit Polyclonal Antibody
别名
SEPT1; DIFF6; PNUTL3; Septin-1; LARP; Peanut-like protein 3; Serologically defined breast cancer antigen NY-BR-24
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1731
Human Swissprot No.
Q8WYJ6
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8WYJ6/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=54204
Mouse Swissprot No.
P42209
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P42209
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=293507
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q5EB96
免疫原
The antiserum was produced against synthesized peptide derived from human SEPT1. AA range:181-230
特异性
Septin 1 Polyclonal Antibody detects endogenous levels of Septin 1 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
septin 1(SEPT1) Homo sapiens This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis and the maintenance of cellular morphology. This gene encodes a protein that can form homo- and heterooligomeric filaments, and may contribute to the formation of neurofibrillary tangles in Alzheimer's disease. Alternatively spliced transcript variants have been found but the full-length nature of these variants has not been determined. [provided by RefSeq, Dec 2012],
组织表达
Expressed at high levels in lymphoid and hematopoietic tissues.
细胞定位
Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Remains at the centrosomes and the nearby microtubules throughout mitosis. Localizes to the midbody during cytokinesis.
功能
function:Involved in cytokinesis .,similarity:Belongs to the septin family.,subunit:May assemble into a multicomponent structure.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
