产品名称
SENP8 Rabbit Polyclonal Antibody
别名
SENP8; DEN1; NEDP1; PRSC2; FKSG8; Sentrin-specific protease 8; Deneddylase-1; NEDD8-specific protease 1; Protease; cysteine 2; Sentrin/SUMO-specific protease SENP8
蛋白名称
Sentrin-specific protease 8
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=123228
Human Swissprot No.
Q96LD8
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q96LD8/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=71599
Mouse Swissprot No.
Q9D2Z4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9D2Z4
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=315723
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q5FVJ8
免疫原
The antiserum was produced against synthesized peptide derived from human SENP8. AA range:161-210
特异性
SENP8 Polyclonal Antibody detects endogenous levels of SENP8 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a cysteine protease that is a member of the sentrin-specific protease family. The encoded protein is involved in processing and deconjugation of the ubiquitin-like protein termed, neural precursor cell expressed developmentally downregulated 8. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009],
组织表达
Broadly expressed, with highest levels in kidney and pancreas.
功能
function:Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53.,similarity:Belongs to the peptidase C48 family.,tissue specificity:Broadly expressed, with highest levels in kidney and pancreas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
