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SENP7 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT4241
产品名称
SENP7 Rabbit Polyclonal Antibody
别名
SENP7; KIAA1707; SSP2; SUSP2; Sentrin-specific protease 7; SUMO-1-specific protease 2; Sentrin/SUMO-specific protease SENP7
类别
常规抗体
基因名称
SENP7
蛋白名称
Sentrin-specific protease 7
推荐应用
WB
反应种属
Human,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
57337
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57337
Human Swissprot No.
Q9BQF6
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9BQF6/entry
Mouse Gene ID
66315
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=66315
Mouse Swissprot No.
Q8BUH8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BUH8
免疫原
The antiserum was produced against synthesized peptide derived from human SENP7. AA range:991-1040
特异性
SENP7 Polyclonal Antibody detects endogenous levels of SENP7 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
预测分子量
112kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009],
组织表达
Brain,Epithelium,Fetal kidney,Placenta,
细胞定位
Cytoplasm .
功能
alternative products:Experimental confirmation may be lacking for some isoforms,caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full-length SUMO proteins to their mature forms.,similarity:Belongs to the peptidase C48 family.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using SENP7 Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from HUVEC cells, using SENP7 Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using SENP7 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).

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