产品名称
Septin 3 Rabbit Polyclonal Antibody
别名
SEPT3; SEP3; Neuronal-specific septin-3
蛋白名称
Neuronal-specific septin-3
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55964
Human Swissprot No.
Q9UH03
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9UH03/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24050
Mouse Swissprot No.
Q9Z1S5
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9Z1S5
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56003
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q9WU34
免疫原
The antiserum was produced against synthesized peptide derived from human SEPT3. AA range:136-185
特异性
Septin 3 Polyclonal Antibody detects endogenous levels of Septin 3 protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
septin 3(SEPT3) Homo sapiens This gene belongs to the septin family of GTPases. Members of this family are required for cytokinesis. Expression is upregulated by retinoic acid in a human teratocarcinoma cell line. The specific function of this gene has not been determined. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm. Cytoplasm, cytoskeleton . Cell junction, synapse .
功能
function:Involved in cytokinesis .,induction:Up-regulated during neuronal differentiation.,PTM:Phosphorylated by PKG on serine residues. Phosphorylated by PKG on Ser-91.,similarity:Belongs to the septin family.,subcellular location:Localizes in synaptosomes at dendritic synapses of neurons. Localizes within presynaptic terminals of neurons.,subunit:May assemble into a multicomponent structure.,tissue specificity:Brain specific.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
