产品名称
Secretin Receptor Rabbit Polyclonal Antibody
别名
SCTR; Secretin receptor; SCT-R
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6344
Human Swissprot No.
P47872
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P47872/entry
Mouse Swissprot No.
Q5FWI2
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q5FWI2
免疫原
The antiserum was produced against synthesized peptide derived from human SCTR. AA range:100-149
特异性
Secretin Receptor Polyclonal Antibody detects endogenous levels of Secretin Receptor protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
secretin receptor(SCTR) Homo sapiens The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism. [provided by RefSeq, Jul 2008],
组织表达
Brain,Kidney,Lung,Pancreas,
细胞定位
Cell membrane ; Multi-pass membrane protein .
信号通路
Neuroactive ligand-receptor interaction;
功能
function:This is a receptor for secretin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,similarity:Belongs to the G-protein coupled receptor 2 family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
