产品名称
Sec23B Rabbit Polyclonal Antibody
别名
SEC23B; Protein transport protein Sec23B; SEC23-related protein B
蛋白名称
Protein transport protein Sec23B
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10483
Human Swissprot No.
Q15437
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q15437/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27054
Mouse Swissprot No.
Q9D662
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9D662
免疫原
The antiserum was produced against synthesized peptide derived from human Sec23B. AA range:495-544
特异性
Sec23B Polyclonal Antibody detects endogenous levels of Sec23B protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010],
组织表达
Ubiquitously expressed.
细胞定位
Cytoplasmic vesicle, COPII-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytosol .
功能
function:Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.,similarity:Belongs to the SEC23/SEC24 family. SEC23 subfamily.,subunit:COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
