产品名称
SCAMP1 Rabbit Polyclonal Antibody
别名
SCAMP1; SCAMP; Secretory carrier-associated membrane protein 1; Secretory carrier membrane protein 1
蛋白名称
Secretory carrier-associated membrane protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9522
Human Swissprot No.
O15126
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O15126/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=107767
Mouse Swissprot No.
Q8K021
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K021
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29521
Rat Swissprot Link
http://www.uniprot.org/uniprot/P56603
免疫原
The antiserum was produced against synthesized peptide derived from human SCAMP1. AA range:273-322
特异性
SCAMP1 Polyclonal Antibody detects endogenous levels of SCAMP1 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene product belongs to the SCAMP family of proteins, which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that these protein family members may function at the same site during vesicular transport rather than in separate pathways. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014],
组织表达
Widely expressed, with highest expression in brain.
细胞定位
Golgi apparatus, trans-Golgi network membrane ; Multi-pass membrane protein . Recycling endosome membrane ; Multi-pass membrane protein .
功能
function:Functions in post-Golgi recycling pathways. Acts as a recycling carrier to the cell surface.,similarity:Belongs to the SCAMP family.,subunit:Interacts with AP1GBP1 and ITSN1 (By similarity). Interacts with SLC9A7.,tissue specificity:Widely expressed, with highest expression in brain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
