产品名称
SCAF1 Rabbit Polyclonal Antibody
别名
SCAF1; SFRS19; SRA1; Splicing factor; arginine/serine-rich 19; SR-related and CTD-associated factor 1; SR-related-CTD-associated factor; SCAF; Serine arginine-rich pre-mRNA splicing factor SR-A1; SR-A1
蛋白名称
Splicing factor arginine/serine-rich 19
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=58506
Human Swissprot No.
Q9H7N4
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9H7N4/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=233208
Mouse Swissprot No.
Q5U4C3
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q5U4C3
免疫原
The antiserum was produced against synthesized peptide derived from human SFRS19. AA range:41-90
特异性
SCAF1 Polyclonal Antibody detects endogenous levels of SCAF1 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
function:May function in pre-mRNA splicing.,induction:Up-regulated by estrogens, androgens and glucocorticoids.,similarity:Belongs to the splicing factor SR family.,subunit:Interacts with POLR2A.,tissue specificity:Ubiquitous. Highly expressed in fetal brain and liver, poorly expressed in salivary gland, heart, skin and ovary. Expressed in colorectal carcinomas and ovarian cancers. Overexpressed in colorectal carcinomas as compared to normal colonic mucosa.,
组织表达
Ubiquitous. Highly expressed in fetal brain and liver, poorly expressed in salivary gland, heart, skin and ovary. Expressed in colorectal carcinomas and ovarian cancers. Overexpressed in colorectal carcinomas as compared to normal colonic mucosa.
功能
function:May function in pre-mRNA splicing.,induction:Up-regulated by estrogens, androgens and glucocorticoids.,similarity:Belongs to the splicing factor SR family.,subunit:Interacts with POLR2A.,tissue specificity:Ubiquitous. Highly expressed in fetal brain and liver, poorly expressed in salivary gland, heart, skin and ovary. Expressed in colorectal carcinomas and ovarian cancers. Overexpressed in colorectal carcinomas as compared to normal colonic mucosa.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
