产品名称
LETM1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/3954
Human Swissprot No.
O95202
Human Swissprot Link
https://www.uniprot.org/uniprotkb/O95202/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/56384
Mouse Swissprot No.
Q9Z2I0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Z2I0
Rat Gene Link
https://www.uniprot.org/uniprot/305457
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5XIN6
免疫原
Synthesized peptide derived from human LETM1 AA range: 574-624
特异性
This antibody detects endogenous levels of LETM1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein that is localized to the inner mitochondrial membrane. The protein functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4. Related pseudogenes have been identified on chromosomes 8, 15 and 19. [provided by RefSeq, Oct 2009],
细胞定位
Mitochondrion inner membrane ; Single-pass membrane protein .
功能
similarity:Contains 1 EF-hand domain.,similarity:Contains 1 LETM1 domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.