产品名称
S-100A5 Rabbit Polyclonal Antibody
别名
S100A5; S100D; Protein S100-A5; Protein S-100D; S100 calcium-binding protein A5
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6276
Human Swissprot No.
P33763
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P33763/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20199
Mouse Swissprot No.
P63084
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P63084
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=295211
Rat Swissprot Link
http://www.uniprot.org/uniprot/P63083
免疫原
The antiserum was produced against synthesized peptide derived from human S100A5. AA range:34-83
特异性
S-100A5 Polyclonal Antibody detects endogenous levels of S-100A5 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
S100 calcium binding protein A5(S100A5) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted regions of the adult brain. [provided by RefSeq, Jul 2008],
细胞定位
nucleus,neuronal cell body,
功能
similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
