产品名称
S-100A3 Rabbit Polyclonal Antibody
别名
S100A3; S100E; Protein S100-A3; Protein S-100E; S100 calcium-binding protein A3
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6274
Human Swissprot No.
P33764
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P33764/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20197
Mouse Swissprot No.
P62818
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P62818
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=114216
Rat Swissprot Link
http://www.uniprot.org/uniprot/P62819
免疫原
The antiserum was produced against synthesized peptide derived from human S100A3. AA range:26-75
特异性
S-100A3 Polyclonal Antibody detects endogenous levels of S-100A3 protein.
稀释度
WB 1:500-2000 IHC 1:100 - 1:300. ELISA: 1:40000. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
S100 calcium binding protein A3(S100A3) Homo sapiens The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has the highest content of cysteines of all S100 proteins, has a high affinity for Zinc, and is highly expressed in human hair cuticle. The precise function of this protein is unknown. [provided by RefSeq, Jul 2008],
组织表达
Skin specific, specifically expressed at the inner endocuticle of hair fibers.
功能
function:Binds both calcium and zinc. Probably binds 2 zinc ions per molecule. May be involved in calcium-dependent cuticle cell differentiation and hair shaft formation.,similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,subunit:Homodimer.,tissue specificity:Skin specific.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
