产品名称
RNF130 Rabbit Polyclonal Antibody
别名
RNF130; E3 ubiquitin-protein ligase RNF130; Goliath homolog; H-Goliath; RING finger protein 130
蛋白名称
E3 ubiquitin-protein ligase RNF130
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=55819
Human Swissprot No.
Q86XS8
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q86XS8/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=59044
Mouse Swissprot No.
Q8VEM1
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8VEM1
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=652955
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q6Y290
免疫原
The antiserum was produced against synthesized peptide derived from human RNF130. AA range:231-280
特异性
RNF130 Polyclonal Antibody detects endogenous levels of RNF130 protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
ring finger protein 130(RNF130) Homo sapiens The protein encoded by this gene contains a RING finger motif and is similar to g1, a Drosophila zinc-finger protein that is expressed in mesoderm and involved in embryonic development. The expression of the mouse counterpart was found to be upregulated in myeloblastic cells following IL3 deprivation, suggesting that this gene may regulate growth factor withdrawal-induced apoptosis of myeloid precursor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
组织表达
Ubiquitously expressed. Highly expressed in leukocytes. Not expressed in erythroblasts.
细胞定位
Membrane ; Single-pass type I membrane protein . Cytoplasm .
功能
function:May have a role during the programmed cell death of hematopoietic cells.,similarity:Contains 1 PA (protease associated) domain.,similarity:Contains 1 RING-type zinc finger.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
