产品名称
Ribosomal Protein S8 Rabbit Polyclonal Antibody
别名
RPS8; OK/SW-cl.83; 40S ribosomal protein S8
蛋白名称
40S ribosomal protein S8
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6202
Human Swissprot No.
P62241
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P62241/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=100040298
Mouse Swissprot No.
P62242
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P62242
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=297756
Rat Swissprot Link
http://www.uniprot.org/uniprot/P62243
免疫原
The antiserum was produced against synthesized peptide derived from human RPS8. AA range:111-160
特异性
Ribosomal Protein S8 Polyclonal Antibody detects endogenous levels of Ribosomal Protein S8 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
宿主
Polyclonal, Rabbit,IgG
背景介绍
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S8E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal tumors and colon polyps compared to matched normal colonic mucosa has been observed. This gene is co-transcribed with the small nucleolar RNA genes U38A, U38B, U39, and U40, which are located in its fourth, fifth, first, and second introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008],
组织表达
Colon adenocarcinoma,Liver,Placenta,Thalamus,Uterus,
细胞定位
Cytoplasm . Membrane ; Lipid-anchor . Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
功能
similarity:Belongs to the ribosomal protein S8e family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.