BD-PT4118

Ribosomal Protein L7 Rabbit Polyclonal Antibody

RPL7; 60S ribosomal protein L7

常规抗体

RPL7

60S ribosomal protein L7

WB

Human,Mouse,Rat,Cat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

6129

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6129

P18124

http://www.uniprot.org/uniprotkb/P18124/entry

19989

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=19989

P14148

http://www.uniprot.org/uniprot/P14148

P05426

http://www.uniprot.org/uniprot/P05426

The antiserum was produced against synthesized peptide derived from human RPL7. AA range:199-248

Ribosomal Protein L7 Polyclonal Antibody detects endogenous levels of Ribosomal Protein L7 protein.

WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

32kD

-20°C/1 year

Polyclonal, Rabbit,IgG

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical

Bone marrow,Eye,Fibroblast,Hepatoma,Lung,Mammary gland,Muscle,Pancreas,Skin,

nucleus,nucleolus,cytoplasm,cytosol,ribosome,focal adhesion,membrane,cytosolic large ribosomal subunit,intracellular ribonucleoprotein complex,extracellular exosome,

Ribosome;

function:Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs.,similarity:Belongs to the ribosomal protein L30P family.,subunit:Homodimer.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.