产品名称
Rhophilin Rabbit Polyclonal Antibody
别名
RHPN1; KIAA1929; Rhophilin-1; GTP-Rho-binding protein 1
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=114822
Human Swissprot No.
Q8TCX5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q8TCX5/entry
Mouse Swissprot No.
Q61085
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q61085
免疫原
The antiserum was produced against synthesized peptide derived from human RHPN1. AA range:474-523
特异性
Rhophilin Polyclonal Antibody detects endogenous levels of Rhophilin protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
domain:The PDZ domain mediates interaction with ROPN1.,function:Has no enzymatic activity. May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules.,similarity:Belongs to the RHPN family.,similarity:Contains 1 BRO1 domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 REM (Hr1) repeat.,subunit:Binds specifically to GTP-Rho. Interacts with ROPN1.,
功能
domain:The PDZ domain mediates interaction with ROPN1.,function:Has no enzymatic activity. May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules.,similarity:Belongs to the RHPN family.,similarity:Contains 1 BRO1 domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 REM (Hr1) repeat.,subunit:Binds specifically to GTP-Rho. Interacts with ROPN1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.