产品名称
RhoBTB1/2 Rabbit Polyclonal Antibody
别名
RHOBTB1; KIAA0740; Rho-related BTB domain-containing protein 1; RHOBTB2; DBC2; KIAA0717; Rho-related BTB domain-containing protein 2; Deleted in breast cancer 2 gene protein; p83
蛋白名称
Rho-related BTB domain-containing protein 1/2
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23221
Human Swissprot No.
O94844/Q9BYZ6
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O94844/entry
Mouse Gene ID
69288/246710
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=69288
免疫原
The antiserum was produced against synthesized peptide derived from human RHBT2. AA range:61-110
特异性
RhoBTB1/2 Polyclonal Antibody detects endogenous levels of RhoBTB1/2 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008],
组织表达
Ubiquitous, with highest levels in skeletal muscle, placenta, testis, stomach, and kidney, followed by uterus and adrenal gland. Expressed in a variety of fetal tissues.
细胞定位
intracellular,cytosol,plasma membrane,
功能
similarity:Belongs to the small GTPase superfamily. Rho family.,similarity:Contains 2 BTB (POZ) domains.,tissue specificity:Ubiquitous, with highest levels in skeletal muscle, placenta, testis, stomach, and kidney, followed by uterus and adrenal gland. Expressed in a variety of fetal tissues.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.