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RhoBTB1/2 Rabbit Polyclonal Antibody

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产品基本信息

产品货号
BD-PT4084
产品名称
RhoBTB1/2 Rabbit Polyclonal Antibody
别名
RHOBTB1; KIAA0740; Rho-related BTB domain-containing protein 1; RHOBTB2; DBC2; KIAA0717; Rho-related BTB domain-containing protein 2; Deleted in breast cancer 2 gene protein; p83
类别
常规抗体
基因名称
RHOBTB1/RHOBTB2
蛋白名称
Rho-related BTB domain-containing protein 1/2
推荐应用
WB
反应种属
Human,Mouse
浓度
1 mg/ml
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene ID
23221/9886
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23221
Human Swissprot No.
O94844/Q9BYZ6
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O94844/entry
Mouse Gene ID
69288/246710
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=69288
免疫原
The antiserum was produced against synthesized peptide derived from human RHBT2. AA range:61-110
特异性
RhoBTB1/2 Polyclonal Antibody detects endogenous levels of RhoBTB1/2 protein.
稀释度
WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
预测分子量
83kD
运输及保存条件
-20°C/1 year
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene belongs to the Rho family of the small GTPase superfamily. It contains a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. The protein plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008],
组织表达
Ubiquitous, with highest levels in skeletal muscle, placenta, testis, stomach, and kidney, followed by uterus and adrenal gland. Expressed in a variety of fetal tissues.
细胞定位
intracellular,cytosol,plasma membrane,
功能
similarity:Belongs to the small GTPase superfamily. Rho family.,similarity:Contains 2 BTB (POZ) domains.,tissue specificity:Ubiquitous, with highest levels in skeletal muscle, placenta, testis, stomach, and kidney, followed by uterus and adrenal gland. Expressed in a variety of fetal tissues.,
期货
现货
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Western blot analysis of lysates from HepG2 and HeLa cells, using RHBT2 Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using RhoBTB1/2 Polyclonal Antibody

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