产品名称
RCL Rabbit Polyclonal Antibody
别名
RCL; C6orf108; Deoxyribonucleoside 5'-monophosphate N-glycosidase; c-Myc-responsive protein Rcl
蛋白名称
Deoxyribonucleoside 5'-monophosphate N-glycosidase
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10591
Human Swissprot No.
O43598
Human Swissprot Link
http://www.uniprot.org/uniprotkb/O43598/entry
Mouse Swissprot No.
Q80VJ3
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q80VJ3
免疫原
The antiserum was produced against synthesized peptide derived from human RCL. AA range:1-50
特异性
RCL Polyclonal Antibody detects endogenous levels of RCL protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene was identified on the basis of its stimulation by c-Myc protein. The latter is a transcription factor that participates in the regulation of cell proliferation, differentiation, and apoptosis. The exact function of this gene is not known but studies in rat suggest a role in cellular proliferation and c-Myc-mediated transformation. Two alternative transcripts encoding different proteins have been described. [provided by RefSeq, Jul 2008],
组织表达
Expressed at low levels in brain, colon, lung, peripheral blood leukocytes, placenta, small intestine, and thymus. Expressed at high levels in heart, kidney, liver, skeletal muscle and spleen. Overexpressed in a significant proportion of breast cancers.
细胞定位
Cytoplasm . Nucleus .
功能
caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:May play a role during cellular proliferation and c-Myc-mediated transformation.,tissue specificity:Expression is elevated in lymphoid cells that overexpress c-Myc.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
