产品名称
RASSF4 Rabbit Polyclonal Antibody
别名
RASSF4; AD037; Ras association domain-containing protein 4
蛋白名称
Ras association domain-containing protein 4
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=83937
Human Swissprot No.
Q9H2L5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9H2L5/entry
Mouse Swissprot No.
Q8CB96
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8CB96
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=362423
Rat Swissprot Link
http://www.uniprot.org/uniprot/Q566C5
免疫原
The antiserum was produced against synthesized peptide derived from human RASSF4. AA range:134-183
特异性
RASSF4 Polyclonal Antibody detects endogenous levels of RASSF4 protein.
稀释度
WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
宿主
Polyclonal, Rabbit,IgG
背景介绍
The function of this gene has not yet been determined but may involve a role in tumor suppression. Alternative splicing of this gene results in several transcript variants; however, most of the variants have not been fully described. [provided by RefSeq, Jul 2008],
组织表达
Widely expressed. Frequently down-regulated in tumor cell lines.
功能
function:Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 SARAH domain.,subunit:Interacts directly with activated KRAS in a GTP-dependent manner.,tissue specificity:Widely expressed. Frequently down-regulated in tumor cell lines.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
