BD-PT4011

RASSF2 Rabbit Polyclonal Antibody

RASSF2; KIAA0168; Ras association domain-containing protein 2

常规抗体

RASSF2

Ras association domain-containing protein 2

WB

Human,Mouse,Rat

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

9770

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9770

P50749

http://www.uniprot.org/uniprotkb/P50749/entry

215653

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=215653

Q8BMS9

http://www.uniprot.org/uniprot/Q8BMS9

311437

http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=311437

Q3B7D5

http://www.uniprot.org/uniprot/Q3B7D5

The antiserum was produced against synthesized peptide derived from human RASSF2. AA range:109-158

RASSF2 Polyclonal Antibody detects endogenous levels of RASSF2 protein.

WB 1:500-2000;IHC-p 1:50-300

36kD

-20°C/1 year

Polyclonal, Rabbit,IgG

This gene encodes a protein that contains a Ras association domain. Similar to its cattle and sheep counterparts, this gene is located near the prion gene. Two alternatively spliced transcripts encoding the same isoform have been reported. [provided by RefSeq, Jul 2008],

Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines.

Nucleus. Cytoplasm. Chromosome, centromere, kinetochore . Translocates to the cytoplasm in the presence of STK3/MST2 AND STK4/MST1.

function:Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 SARAH domain.,subunit:Interacts directly with activated KRAS in a GTP-dependent manner.,tissue specificity:Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines.,

现货

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.