产品名称
Rap 2C Rabbit Polyclonal Antibody
别名
RAP2C; Ras-related protein Rap-2c
蛋白名称
Ras-related protein Rap-2c
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=57826
Human Swissprot No.
Q9Y3L5
Human Swissprot Link
http://www.uniprot.org/uniprotkb/Q9Y3L5/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=72065
Mouse Swissprot No.
Q8BU31
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BU31
免疫原
The antiserum was produced against synthesized peptide derived from human RAP2C. AA range:97-146
特异性
Rap 2C Polyclonal Antibody detects endogenous levels of Rap 2C protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the Ras-related protein subfamily of the Ras GTPase superfamily. Members of this family are small GTPases that act as molecular switches to regulate cellular proliferation, differentiation, and apoptosis. This protein has been reported to activate in vitro transcriptional activity of the serum response element. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012],
组织表达
Expressed in liver, skeletal muscle, prostate, uterus, rectum, stomach, and bladder and to a lower extent in brain, kidney, pancreas, and bone marrow. Expressed in mononuclear leukocytes and megakaryocytes.
细胞定位
Cytoplasm . Recycling endosome membrane ; Lipid-anchor ; Cytoplasmic side .
功能
similarity:Belongs to the small GTPase superfamily. Ras family.,tissue specificity:Expressed in mononuclear leukocytes and megakaryocytes. Not detected in platelets.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
