产品名称
Rap 2B Rabbit Polyclonal Antibody
别名
RAP2B; Ras-related protein Rap-2b
蛋白名称
Ras-related protein Rap-2b
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5912
Human Swissprot No.
P61225
Human Swissprot Link
http://www.uniprot.org/uniprotkb/P61225/entry
Mouse Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=74012
Mouse Swissprot No.
P61226
Mouse Swissprot Link
http://www.uniprot.org/uniprot/P61226
Rat Gene Link
http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=170923
Rat Swissprot Link
http://www.uniprot.org/uniprot/P61227
免疫原
The antiserum was produced against synthesized peptide derived from human RAP2B. AA range:98-147
特异性
Rap 2B Polyclonal Antibody detects endogenous levels of Rap 2B protein.
稀释度
WB 1:500-2000;IHC-p 1:50-300
宿主
Polyclonal, Rabbit,IgG
背景介绍
This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated. [provided by RefSeq, Jul 2008],
组织表达
Expressed in red blood cells (at protein level).
细胞定位
Recycling endosome membrane ; Lipid-anchor ; Cytoplasmic side . Associated with red blood cells-released vesicles.
功能
domain:The effector domain mediates the interaction with RUNDC3A.,similarity:Belongs to the small GTPase superfamily. Ras family.,subunit:Interacts with PLCE1. Interacts with SGSM1, SGSM2 and SGSM3. The GTP-bound form of RAP2B interacts with RUNDC3A.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
